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Documents  Barton, Nicholas H. | enregistrements trouvés : 2

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Research talks;Mathematics in Science and Technology;Probability and Statistics

Maladapted individuals can only colonise a new habitat if they can evolve a positive growth rate fast enough to avoid extinction - evolutionary rescue. We use the infinitesimal model to follow the evolution of the growth rate, and find that the probability that a single migrant can establish depends on just two parameters: the mean and genetic variance of fitness. With continued migration, establishment is inevitable. However, above a threshold migration rate, the population may be trapped in a sink state, in which adaptation is held back by gene flow. By assuming a constant genetic variance, we develop a diffusion approximation for the joint distribution of population size and trait mean. Maladapted individuals can only colonise a new habitat if they can evolve a positive growth rate fast enough to avoid extinction - evolutionary rescue. We use the infinitesimal model to follow the evolution of the growth rate, and find that the probability that a single migrant can establish depends on just two parameters: the mean and genetic variance of fitness. With continued migration, establishment is inevitable. However, above a threshold ...

92D15 ; 92D10 ; 92D25

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Research talks;Probability and Statistics

The infinitesimal model is based on the assumption that, conditional on the pedigree, the joint distribution of trait values is multivariate normal, then, selecting parents does not alter the variance amongst offspring. We explain how the infinitesimal model extends to include dominance as well as epistasis. Then, the evolution of a population depends on just a few quantities, which define the components of genetic variance and the inbreeding depression. In practice, the main difficulty in applying the infinitesimal model in the presence of dominance is that one must calculate the probabilities of identity by descent amongst up to four genes, which means that very many identity coefficients must be traced. We show how these coefficients can be calculated and approximated, allowing the infinitesimal model to be applied to help understand the evolutionary consequences of inbreeding depression. The infinitesimal model is based on the assumption that, conditional on the pedigree, the joint distribution of trait values is multivariate normal, then, selecting parents does not alter the variance amongst offspring. We explain how the infinitesimal model extends to include dominance as well as epistasis. Then, the evolution of a population depends on just a few quantities, which define the components of genetic variance and the inbreeding ...

60F05 ; 60K30 ; 92D10

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